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Macau Periodical Index (澳門期刊論文索引)
- Author
- Hong, Kam Wai
- Title
- Lock solution for non-tunneled hemodialysis catheter：recent advances
- Journal Name
- 鏡湖醫學
- Pub. Info
- 2020年6月, 總第42期, 第20卷第1期, pp. 61-63, 53
- Link
- http://www.kwh.org.mo/download/med42.pdf
- Keyword
- Hemodialysis；Lock solution；Non-tunneled hemodialysis catheter
- Abstract
- Objective：This literature review aimed to identify the recent advance on the effectiveness of different non-tunneled hemodialysis catheters (NTHCs) lock solutions. Methods：A literature search was conducted to achieve available articles published from 2010 to 2020 focusing on the latest advancements for the lock solution for NTHCs. Ovid MEDLINE，PubMed，and Joanna Briggs Institute Database were searched，and manual searching of bibliographies was also adopted to enhance the searching. Results：Based on the reviewed studies，three primary outcomes were discussed in the light of catheter-related bloodstream infection (CRBSI)，exit-site infection，and catheter patency，respectively. The literature suggested a significant difference between heparin and novel lock solution such as citrate with antimicrobials，as a catheter lock solution in terms of the survival duration of CRBSI in patients with NTHCs in critically ill patients. No significant difference in the exit-site infection and the preservation of catheter patency was found in the included studies. However，due to the variation of citrate concentration and the combination of antimicrobials，the efficacy and safety of antimicrobia lock solutions remained unclear. Conclusion：Different citrate lock solutions were likely superior to the conventional heparin lock solution in terms of CRBSI，exit-site infection，and maintenance of catheter patency. Paragraph Headings： 1. Background 2. Methods 3. Results 3.1. Catheter-related bloodstream infection 3.2. Exit-site infection 3.3. Catheter patency 4. Discussion 5. Conclusion