It is commonly argued that the rise of China, with its increasing economic growth and military defense spending during 20th century, have proposed significant threat to the United States (U.S.) and that U.S. strategy no longer works for a new rising China. While this may be correct, in this thesis, I present how power transition theory and economic interdependence shaken the current U.S. global status and attention has shifted towards Asia. I integrated three strategies: Multilateralism, Offshore Balancing and Hedging, analysis and made comparisons among them to sum up a better strategic option for the U.S. decision making on a rising China. Results indicated that the number of states involvement is crucial to determine the decision making process in the strategy of Multilateralism. Hence, it is shown to be more applicable within Southeast Asia. Whereas for an offshore balancing strategy, states motivation became one biggest concern. Their willingness for deterrence will affect future global relations as this strategy may impose an illusion to a Chinese isolation. In return, states cooperation and their capacity may assist with diminishing the current Chinese threat. And consequently, to sum up for a better strategic option, hedging becomes much more favorable to enhance the future of Sino-U.S relations.