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Macau Periodical Index (澳門期刊論文索引)
- Author
- Neng, Seong In；Chan, In Ha；Cheong, Tak Hong
- Title
- Macau local data of lung cancer and treatment prospect of advanced lung cancer
- Journal Name
- 鏡湖醫學
- Pub. Info
- 2022年12月, 總第47期, 第22卷第2期, pp. 17-19, 14
- Link
- https://mjokw.magtechjournal.com/CN/Y2022/V22/I2
- Keyword
- Lung cancer；Incidence；Molecular type；Target therapy
- Abstract
- Objective：Lung cancer has been a challenging problem in Macaufor the last 10 years, and at least half of patients are at an advanced stage when they are diagnosed. Target therapy worked as a new direction to advance stage lung cancer patients. This article intended to realize its effect of target therapy in the Macau area. Methods：Lung cancer has been a challenging problem in Macau for the last 10 years, and at least half of patients are at an advanced stage when they are diagnosed. Target therapy worked as a new direction to advance stage lung cancer patients. This article intends to realize the effect of target therapy in the Macau area. Results：In the final analysis, annual new lung cancer cases increased and ranked as the top cause of death among tumor patients in the past ten years in Macau. Half of the Macau lung cancer cases were smokers. In addition, nonsmoking female lung cancer patients grow up rapidly. Lung adenocarcinoma was the main histological type in Macau in recent decades. EGFR and ALK gene mutations are common genetic types, and approximately 40% of lung adenocarcinoma patients benefit from targeted therapy because of molecular test implementation. Overall survival and the 5-year survival rate clinically increased in the targeted therapy and chemo-targeted therapy groups. Better drug compliance was observed after target therapy was introduced in Macau. We are looking forward to the development of molecular biology and the corresponding drugs. Conclusion：Smoking cessation should be continuously promoted in Macau. Molecular testingworked as a routine examination of lung adenocarcinoma patients to improve the survival rate. The effect of targeted therapy in lung cancer patients is encouraging, and it is worth expecting more genotype-based or phenotype-based treatments to improve the survival rate of lung cancer patients in Macau. Paragraph Headings： 1. Introduction 2. Incidence，Age distribution，Staging 3. Effect of lung cancer treatment 4. Conclusion Tables： 1. Screening conditions 2. Overall survival and 5-year survival rates in each group Figures： 1. New lung cancer cas es in Macau annually 2. Age distribution of lung cancer cases in the past 10 years 3. Staging of lung cancer Figure 4. Histological results of lung cancer in Macau 5. Gene mutation case in lung adenocarcinoma 6. Gene mutation results in female lung adenocarcinoma cases 7. Gene mutation results in male lung adenocarcinoma cases