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Macau Periodical Index (澳門期刊論文索引)

Author
Ma, Mu Ti Jiang; Wen, Hao; Chen, Qi Long; Di-Li, Bai Er
Title
Clinical analysis of timing for laparotomy and prognosis of severe acute pancreatitis
Journal Name
澳門醫學雜誌
Pub. Info
2005年3月26日, Vol.5, No.1, pp. 15-19
Keyword
Pancreatitis;Surgical operation;Complication;Prognosis
Abstract
Objective: Severe acute pancreatitis (SAP) occurred in 15%-20% of patients with acute pancreatitis, which was morphologically characterized by extra and intrapancreatic necrosis and associated with single or multiple organ failure syndrome (MOFS). It is generally accepted that surgery can be considered as major therapy form of infected pancreatic necorsis. However, timing and indication have been still controversial. In this retrospective study, the effect of different kinds of treatment were evaluated, and relationship between timing of laparotomy and prognosis were analyzed. Methods: A total of 79 consecutive SAP patients were admitted to our hospital form January 1999 to January 2004. All patients were diagnosed by Computed Tomography and clinical testing parameter or laparotomy (Some cases had to perform laparotomy with clearance of necrotic pancreas tissues and drainage). Timing of laparotomy, surgical complications and mortality rate were discussed. Results: Complication rates in group of early, delayed laparotomy and consercative treatment were 33.33%, 11.11%, 7.14% respectively. Their mortality rate were 15.15%, 5.56%, 3.57% respectively. Conclusion: Strategy in management of SAP was an important factor influencing the prognosis of SAP. Indevidual treatment (including delayed surgery and conservative form) in SAP may have good prognosis (with low complication and mortality rate). Paragraph Headings: 1. Clinical Data (Patients and Methods) 1.1. General material 1.2. Perioperative management 1.3. Statistical analysis 2. Results 3. Discussion 4. Conclusion Tables: 1. Complication and mortality rate in different kind of SAP 2. Complication rate of laparotomy and conservative management 3. Mortality rate of laparotomy and conservative management